Antioxidant Effects of a Cinnamon Extract in People with Impaired Fasting Glucose That Are Overweight or Obese
Rates of free radical formation are increased in obesity [I]. In people that are obese, the leading causes of oxidative stress have been identified as hyperglycemia, insulin resistance, increased tissue lipid levels, inadequate antioxidant defenses, enzymatic sources within the endothelium and chronic inflammation [2]. Conversely, oxidative stress is presently accepted as a likely causative factor in the development of insulin resistance which is present in obesity [3]. The mechanisms leading to the insulin cascade down-regulation in cells subjected to oxidative stress involves increased serine/threonine phosphorylation of insulin receptor substrate-I (IRS]), impaired insulin-stimulated redistribution of IRS 1 and phosphatidylinositol-kinase between cytosol and.... Download
FAQ on coumarin in cinnamon and other foods
Coumarin is a flavouring substance which is contained in relatively high concentrations in cinnamon varieties collectively known as "Cassia cinnamon". In especially sensitive persons, even comparatively small quantities of coumarin can cause liver damage, although the effect is usually reversible. Isolated coumarin must not be added to foods. However, to flavour foods, coumarin-containing plant parts may be used. For cinnamon-containing foods, new maximum permissible coumarin levels have been in place in the European Union since 2011. In contrast, there are no limit values for cinnamon as a spice..... Download
Cinnamon: A Multifaceted Medicinal Plant
The bark of various cinnamon species is one of the most important and popular spices used worldwide not only for cookingbutalsointraditionalandmodernmedicines.Overall,approximately250specieshavebeenidentifiedamongthe cinnamongenus,withtreesbeingscatteredallovertheworld .... Download
Cinnamon Improves Glucose and Lipids of People With Type 2 Diabetes
OBJECTIVE- The objective of this study was to determine whether cinnamon improves blood glucose, triglyceride, total cholesterol, HDL cholesterol, and LDL cholesterol levels in people with type 2 diabetes. RESEARCHDESIGNANDMETHODS- Atotalof60peoplewithtype2diabetes,30 men and 30 women aged 52.2 6.32 years, were divided randomly into six groups. Groups 1, 2,and3consumed1,3,or6gofcinnamondaily,respectively,andgroups4,5,and6weregiven placebo capsules corresponding to the number of capsules consumed for the three levels of cinnamon. The cinnamon was consumed for 40 days followed by a 20-day washout period...... Download
Cinnamon - IntroductIon
Cinnamon tree is a small evergreen tree belonging to the laurel family or Lauraceae. The bark of the tree is dried and ground and used as spice. Cinnamon is among the world's most widely used spices and is relatively inexpensive. There are two main varieties of cinnamon: Cinnamomum cassia and Cinnamomum verum or C. zeylanicum.... Download
Effectiveness of Cinnamon for Lowering Hemoglobin A1C in Patients with Type 2 Diabetes: A Randomized, Controlled Trial
As the worldwide incidence of diabetes increases, the search for dietary adjuncts to treat this lifealtering disease has become far ranging. Cinnamon is purported to be a natural insulin sensitizer, with adverse events of perioral dermatitis and stomatitis reported uncommonly with high intake. ..... Download
Effects of Consumption of Cinnamon on Blood Glucose and Lipid profile of the Patients of Type 2 Diabetes
It is postulated that spices may play a role in control of blood sugar level. Spices such as cinnamon, cloves, bay leaves, and turmeric display insulin-enhancing activity in vitro [12,3]. Aqueous extracts from cinnamon have been shown to increase in vitro glucose uptake and glycogen synthesis and to increase phosphorylation of the insulin receptor; in addition, these cinnamon extracts are likely to aid in triggering the insulin cascade system [11,12]. Because insulin also plays a key role in lipid metabolism, we postulated that consumption of cinnamon would lead to improved glucose and blood lipids in vivo..... Download
Medicinal properties of 'true' cinnamon (Cinnamonum zeylanicum): a systematic review
Medicinal properties of 'true' cinnamon (Cinnamonum zeylanicum): a systematic review..... Download
New insights into coumarin contained in cinnamon
The Federal Institute for Risk Assessment (BfR) has updated its opinion dated 16 June 2006 on coumarin on the basis of new data. Over the last few years new insights, especially on bioavailability and exposure, have been gained. The new European limit values in effect since January 2011 still applies to coumarin in certain ready-to-eat foods.... Download
Antioxidant Effects of a Cinnamon Extract in People with Impaired Fasting Glucose That Are Overweight or Obese
Rates of free radical formation are increased in obesity [I]. In people that are obese, the leading causes of oxidative stress have been identified as hyperglycemia, insulin resistance, increased tissue lipid levels, inadequate antioxidant defenses, enzymatic sources within the endothelium and chronic inflammation [2]. Conversely, oxidative stress is presently accepted as a likely causative factor in the development of insulin resistance which is present in obesity [3]. The mechanisms leading to the insulin cascade down-regulation in cells subjected to oxidative stress involves increased serine/threonine phosphorylation of insulin receptor substrate-I (IRS]), impaired insulin-stimulated redistribution of IRS 1 and phosphatidylinositol-kinase between cytosol and ..... Download